Does Px affect cortisol levels in the body?Updated 8 days ago

Caffeine consumption is known to increase cortisol levels; however, specific research comparing the impact of paraxanthine—the primary metabolite of caffeine—on cortisol levels relative to caffeine is limited. One study indicated that paraxanthine may have a less pronounced effect on blood pressure compared to caffeine, suggesting potential differences in physiological responses. Nonetheless, direct comparisons of their effects on cortisol secretion are not well-documented.

This may be why Px is considered anxiolytic, whereas caffeine is anxiogenic (increases anxiety).